Hepatosplenic candidiasis with generalized Cutaneous nodular lesions: A case report Ciltte yaygın nodüler lezyonlarla birliktelik gösteren hepatosplenik kandidiyazis: Olgu sunumu

Karakaş A., Tutar E., Tokuç G., Öktem S., BORAN P.

Cocuk Enfeksiyon Dergisi, vol.7, no.1, pp.39-42, 2013 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.5152/ced.2013.09
  • Journal Name: Cocuk Enfeksiyon Dergisi
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.39-42
  • Keywords: Child, Hepatosplenic candidiasis, Neuroblastoma
  • Istanbul Medipol University Affiliated: No


Hepatosplenic candidiasis (HSC), also commonly known as chronic disseminated candidiasis, is a distinct form of disseminated Candida supp. infection, with predominant involvement of the liver, spleen and occasionally the kidneys. It is detected with increasing frequency in patients who developed neutropenia after chemotherapy in childhood cancers. A definitive diagnosis is made by producing the pathogen in culture or showing the pathogen in biopsy specimens. The basic approach in treatment is the use of parenteral amphothericine B. In this paper, a case of a 7 year old patient who developed a large number of nodular lesions on his back and arms in febrile neutropenic episodes while receiving chemotherapy with a diagnosis of stage 4 neuroblastoma is presented. The patient, who was diagnosed with the HSC after radiological tests and blood cultures but did not respond to treatment with amphotericin B, was only treated with caspofungin for a long time. © 2013. by Pediatric Infectious Diseases Society.