Spread of NDM-1-producing enterobacteriaceae in a neonatal intensive care unit in istanbul, turkey

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Poirel L., YILMAZ M., Istanbullu A., Arslan F., MERT A., Bernabeu S., ...More

Antimicrobial Agents and Chemotherapy, vol.58, no.5, pp.2929-2933, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.1128/aac.02047-13
  • Journal Name: Antimicrobial Agents and Chemotherapy
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2929-2933
  • Istanbul Medipol University Affiliated: Yes

Abstract

Twenty-two consecutive carbapenem-resistant enterobacterial isolates were recovered from patients hospitalized between January and April 2013 in different units at a university hospital in Istanbul, Turkey. These were Klebsiella pneumoniae isolates producing the carbapenemases OXA-48, NDM-1, and KPC-2, Enterobacter cloacae isolates producing NDM-1, and Escherichia coli isolates producing OXA-48. Most of the OXA-48-producing K. pneumoniae and all the NDM-1-producing E. cloacae were clonally related. The NDM-1-producing E. cloacae isolates recovered from a single neonatal intensive care unit corresponded to a single cluster, highlighting the spread of that clone in that setting. Copyright © 2014, American Society for Microbiology.