Intra-Articular platelet-rich plasma injection for the treatment of temporomandibular disorders and a comparison with arthrocentesis

Hanci M., Karamese M., Tosun Z., Aktan T. M., Duman S., Savaci N.

Journal of Cranio-Maxillofacial Surgery, vol.43, no.1, pp.162-166, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1016/j.jcms.2014.11.002
  • Journal Name: Journal of Cranio-Maxillofacial Surgery
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.162-166
  • Keywords: Temporomandibular joint disorder, Internal derangement, Platelet-rich plasma, Arthrocentesis
  • Istanbul Medipol University Affiliated: Yes


Background Temporomandibular joint (TMJ) internal derangements are progressive painful conditions and cause joint dysfunction, joint sound, malocclusion, and locking of the mouth. Conservative and invasive techniques can be used for the treatment of TMJ internal derangements. The objective of the present study was to examine the benefit of an intra-Articular platelet-rich plasma (PRP) injection and to compare this with arthrocentesis. Methods Twenty patients (female: male; 15:5; age 26, 3 ± 9.3 years) for a total of 32 joints with reducible anterior disc dislocation, as confirmed by Magnetic Resonance Imaging (MRI), were divided into two groups. PRP was used for the study group, and arthrocentesis was used for the control group. Pain intensity, maximal interincisal opening, and TMJ sounds were assessed and compared for evaluation of treatment success. Results There was a statistically significant reduction in pain intensity and joint sound and an increase in mouth opening in the study group when compared with the control group. Conclusions This study shows that intra-Articular PRP injection for the treatment of reducible disc displacement of the TMJ is a more effective method than arthrocentesis.