Advanced ultrasound in the diagnosis of prostate cancer

Correas J., Halpern E. J., Barr R. G., Ghai S., Walz J., Bodard S., ...More

World Journal of Urology, vol.39, no.3, pp.661-676, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.1007/s00345-020-03193-0
  • Journal Name: World Journal of Urology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, Gender Studies Database, MEDLINE
  • Page Numbers: pp.661-676
  • Keywords: Prostate cancer diagnosis, Micro-ultrasound, mp-MRI, mp-US, Prostate US elastography, Contrast-enhanced US, Fusion imaging, Prostate biopsy, Dispersion imaging
  • Istanbul Medipol University Affiliated: Yes


The diagnosis of prostate cancer (PCa) can be challenging due to the limited performance of current diagnostic tests, including PSA, digital rectal examination and transrectal conventional US. Multiparametric MRI has improved PCa diagnosis and is recommended prior to biopsy; however, mp-MRI does miss a substantial number of PCa. Advanced US modalities include transrectal prostate elastography and contrast-enhanced US, as well as improved B-mode, micro-US and micro-Doppler techniques. These techniques can be combined to define a novel US approach, multiparametric US (mp-US). Mp-US improves PCa diagnosis but is not sufficiently accurate to obviate the utility of mp-MRI. Mp-US using advanced techniques and mp-MRI provide complementary information which will become even more important in the era of focal therapy, where precise identification of PCa location is needed.