Being Small for Gestational Age Affect Neurodevelopmental Outcomes in Very Preterm Infants Gestasyon Haftasına Göre Küçük Olmak Prematüre Bebeklerde Nörogelişimsel Sonuçları Olumsuz Etkiler

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Ceran B., BÜYÜKTİRYAKİ M., Okman E., Şimşek G. K., Kutman H. G. K., Konuk Z. Ü., ...Daha Fazla

Guncel Pediatri, cilt.20, sa.3, ss.331-338, 2022 (ESCI, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4274/jcp.2022.05902
  • Dergi Adı: Guncel Pediatri
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.331-338
  • Anahtar Kelimeler: Neurodevelopmental delay, prematurity, small for gestational age
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

Introduction: There is insufficient data on neurodevelopmental outcomes of infants small for gestational age (SGA) with ≤30 weeks of gestation. The aim of our study was to compare the neurodevelopmental outcomes of preterm infants who are ≤30 weeks, in terms of being SGA or appropriate for gestational age (AGA). Materials and Methods: The data of infants who were born at ≤30 GW, were evaluated retrospectively. Neurological examinations and developmental assessment using Bayley Scales of Infant Development 2nd edition was performed at the corrected age of 18-24 months. Results: The data of 228 infants of whom 65 were SGA and 163 were AGA was evaluated in terms of neurodevelopment at the corrected age of 18-24 months. The mean gestational age (GA) was 28.4±1.1 in both groups (p=0.82) and the mean BW was 810±135 g in the SGA group and 1175±183 g in the AGA group (p<0.001). The SGA group had significantly lower Mental Development Index (p=0.01) and Psychomotor Development Index (p<0.001). In multivariate regression analysis, SGA was identified as an independent risk factor for neurodevelopmental delay (RR: 2.27; p=0.02). Conclusion: Being SGA is a risk factor for neurodevelopmental impairment of preterm infants (≤30 GW).