The aim of this study is to investigate the effect of home science practices on science teacher candidates' critical thinking dispositions, science learning skills, scientific inquiry skills, and learning styles within the scope of open inquiry-based science laboratory practices. For this purpose, the opinions of prospective science teachers within the scope of home science laboratory practices are explored. Participants included 79 third-grade elementary school level (i.e., 8+ year olds) science teacher candidates. Convergent parallel mixed design from mixed methods was used in the study. As a result of the quantitative analysis of the research, a statistically significant difference was found between the pre-test and post-test results of the science teacher candidates' critical thinking dispositions and science learning skills of home science practices. Within the scope of open research inquiry-based science laboratory practices, science teacher candidates' home science practices increased in the informed category at the end of the term in all sub-dimensions of scientific inquiry skills. It was concluded that science teacher candidates experienced shifts in their learning styles relating to (i.e., Diverging, Assimilating, Converging, and Accommodating) their home science practices. The qualitative results of the study were examined based on the following themes: skills, learning environment, application process, and affective changes.