Non-invasive ventilation in children with acute respiratory failure Çocuklarda akut solunum yetmezliǧinde noninvaziv ventilasyon

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Koçkar T., Erdošan F., Gündüz M., Çelebi N., Oktem S., Ceran Ö.

Turkiye Klinikleri Pediatri, vol.25, no.3, pp.146-151, 2016 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.5336/pediatr.2016-50738
  • Journal Name: Turkiye Klinikleri Pediatri
  • Journal Indexes: Scopus
  • Page Numbers: pp.146-151
  • Keywords: Child, Positive-pressure respiration, Respiratory insufficiency
  • Istanbul Medipol University Affiliated: Yes


Objective: Use of non-invasive ventilation (NIV) in children with acute respiratory failure is increasing and gaining importance. The aim of this study is to evaluate the efficacy of NIV in children with acute respiratory failure. Material and Methods: Twenty-nine patients were treated for acute respiratory failure with NIV by using bilevel positive airway pressure (BiPAP) between 2010-2015 in our department. The data from patients were obtained retrospectively. Results: The average age of patients was 8±6 years (2 month-18 years; M/F=19/10). The indications of NIV were Type 1 and Type 2 acute respiratory failure, for which we analyzed data from 16 and 13 patients, respectively. The mean duration of BiPAP usage was 53±45 (10-172) hours. In terms of parameters such as pH, partial carbon dioxide pressure (pCO2), oxygen saturation (SpO2), level of oxygen demand, heart rate and breath per minute (BPM), there were statistical differences between the levels measured at onset, at the 24. hours and at the end of BiPAP application (p <0,05). There was no statistical difference between the patients with failure of NIV and the patients without failure of NIV, in terms of parameters such as pH, pCO2, SpO2, BPM and heart rate. The success of NIV was 65.5%. After BiPAP application, 13 patients no longer needed ventilatory support. Six of the patients were discharged with BiPAP and 10 of the patients needed intubation. Two of the patients who needed mechanical ventilation died (p>0,05). Conclusion: NIV should be preferred in children with acute respiratory failure.