Is the Season of Diagnosis Changing in Children with Type 1 Diabetes Mellitus?

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ÖNAL H., TOPUZ H. Ş., Yılmaz Semerci S., ADAL E.

İstanbul Kanuni Sultan Süleyman Tıp Dergisi, vol.14, no.2, pp.180-185, 2022 (Peer-Reviewed Journal) identifier


Objective: By the effect of global warming, climate model of Turkey is suggested to evolve through semi-arid seasons and to the tropical climate. This study aimed to determine the seasonability for clinical onset of Type 1 diabetes mellitus (T1DM). Method: T1DM patients newly diagnosed between 2014 and 2019 in our pediatric endocrinology department located in Istanbul were included in this study. Clinical onset date and age of diagnosis of diabetes were recorded for each patient. Using the website, regional average rainy days, cloudy days, sunny days, temperature, and ultraviolet index (UVI) were calculated per month for the past 6 years. Results: A total of 659 patients with the new onset T1DM included in this study. A number of new diagnosed patients were 29.1% (192) in winter, 22.8% (150) in spring, 17.6% (116) in summer, and 30.5% (201) in autumn, respectively. No significant effect of the rainy day, cloudy day, sunny day, temperature, and UVI average of the month of diagnosis could be detected on this seasonal shift. Similar results were obtained when 132 patients whose under 4 years of age at the time of diagnosis were excluded from the study data. Conclusion: Although weather conditions seemed to have no considerable effect on this seasonal shift, the T1DM onset in the autumn season was seen to be shifted to the spring season, partially. Further studies including large number of participants are needed for a better understanding of the seasonality of T1DM worldwide.