Effects of leukocyte-platelet rich fibrin on postoperative complications of direct sinus lifting

GÜRLER G., Delilbasi C.

Minerva Stomatologica, vol.65, no.4, pp.207-212, 2016 (Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 65 Issue: 4
  • Publication Date: 2016
  • Journal Name: Minerva Stomatologica
  • Journal Indexes: Scopus
  • Page Numbers: pp.207-212
  • Keywords: Sinus floor augmentation, Postoperative complications, Platelet-rich plasma, Fibrin
  • Istanbul Medipol University Affiliated: Yes


BACKGROUND: Blood products have been widely used in soft tissue and bone regeneration in oral and maxillofacialsurgery. The purpose of this study is to evaluate the effects of leukocyte-platelet rich fibrin (L-PRF) following direct sinuslifting procedure. METHODS: Twenty-eight patients were included in the study. Direct sinus lifting was performed via lateral windowapproach under conscious sedation and local anesthesia. Bony window and sinus floor elevation were performed usingpiezosurgery device. Two groups were formed. In the first group an allogenous bone graft and L-PRF mixture was usedas grafting material. The L-PRF membrane was used to close the lateral window. In the second group, only allogenousbone was used for grafting and resorbable collagen membrane was used to close the lateral window. Pain, swelling, sleeping,eating, phonetics, activities of daily living, missed work days and soft tissue healing were evaluated postoperatively. RESULT S: Data of 24 patients were evaluated. Improvements were seen in the studied parameters in the L-PRF group;however, the difference was not significant between the two groups (P>0.05). CONCLUSIONS: The use of L-PRF and allogenous bone graft in combination with L-PRF membrane does not significantlyimprove postoperative complications following direct sinus lifting.