Flexible bronchoscopy for diagnosis and follow up of childhood endobronchial tuberculosis

Cakir E., Uyan Z. S., Oktem S., Karakoc F., Ersu R., KARADAĞ B. T., ...More

Pediatric Infectious Disease Journal, vol.27, no.9, pp.783-787, 2008 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 9
  • Publication Date: 2008
  • Doi Number: 10.1097/inf.0b013e318170fccc
  • Journal Name: Pediatric Infectious Disease Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.783-787
  • Keywords: Child, Endobronchial tuberculosis, Flexible bronchoscopy
  • Istanbul Medipol University Affiliated: No


Background: In this study, our aim was to determine the clinical and bronchoscopic outcome of the endobronchial tuberculosis (ETB). Methods: Patients with suspected tuberculosis (TB) or TB patients with an inadequate response to 8 weeks of antituberculosis treatment were enrolled in the study. Results: Seventy patients were included to the study and 118 flexible bronchoscopies were performed. ETB was present in 33 (47%) patients. There was isolated compression in 14 cases, caseous lesions in 13, granuloma formation in 6, polypoid lesions in 2, adenopathy protrusion in 1, and mucosal erosion in 1 case. The mean duration of bronchoscopic resolution of endobronchial lesions was 5.50 ± 2.74 months. Mycobacterium tuberculosis was isolated from gastric lavage in 10% and from bronchoalveolar lavage in 12.8% of 70 cases. When both of the procedures were performed concurrently, the isolation rate increased to 20%. Transient hypoxia resolving with nasal O2 was observed in 3 patients as a complication of bronchoscopy. Conclusions: Bronchoscopy offered a safe and rapid means of confirming the diagnosis of ETB. Copyright © 2008 by Lippincott Williams & Wilkins.