Investigation of Hidden Crisis of Prescription Drug Abuse in Turkey: Pregabalin Monitoring


Badur İ., BİLGİN BADUR N., Berk B.

Acta Pharmaceutica Sciencia, cilt.60, sa.4, ss.313-323, 2022 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.23893/1307-2080.aps6021
  • Dergi Adı: Acta Pharmaceutica Sciencia
  • Derginin Tarandığı İndeksler: Scopus, EMBASE
  • Sayfa Sayıları: ss.313-323
  • Anahtar Kelimeler: controlled drug pharmaco-economy, drug abuse, pregabalin, prescription drug monitoring
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

This is a cross-sectional retrospective observational national study. Abuse/misuse of the pregabalin and related parameters analyzed. Pregabalin was mostly pre-scribed by general practitioners (26.2%). Pregabalin prescribing frequencies of other physicians were as follows, respectively: neurology (14.1%); mental health and illness (12%); physical therapy and rehabilitation (8.8%); internal medicine (4.8%). Accordingly, pregabalin (811.954box) and paracetamol, combinations excl. psycholeptics (1,131,069box) were the first two sales. In total cost of sales, pre-gabalin (57,721,322.00 TL) and methylphenidate (41,915,196.00 TL) were the top two sales rankings. According to the disposal results of ILAYS pharmaceuticals in 2020, pregabalin (2693box per year) and morphine (862box per year) were the most disposed drugs. It was determined that the frequency of pregabalin was fol-lowed by gabapentin. In conclusion, our study reveals the extent of abuse of prega-balin in Turkey with its data.